소장자료

Drug-DNA Interaction Protocols [electronic resource]

  • Fox, Keith R. editor.
  • 2010
Drug-DNA Interaction Protocols [electronic resource]
  • 자료유형
    단행본
  • 서명/저자사항
    Drug-DNA Interaction Protocols[electronic resource] / edited by Keith R. Fox.
  • 개인저자
    Fox, Keith R., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    IX, 311 p. 103 illus., 1 illus. in color. : online resource.
  • 총서명
    Methods in Molecular Biology, Methods and Protocols,1064-3745 ; 613
  • 내용주기
    Quantitative Analysis of Small Molecule?밡ucleic Acid Interactions with a Biosensor Surface and Surface Plasmon Resonance Detection -- Thermal Melting Studies of Ligand DNA Interactions -- Circular and Linear Dichroism of Drug-DNA Systems -- Drug Binding to DNA?RNA Hybrid Structures -- Quantification of Binding Data Using Capillary Electrophoresis -- Determination of Equilibrium Association Constants of Ligand?밆NA Complexes by Electrospray Mass Spectrometry -- Detection of Adriamycin-DNA Adducts by Accelerator Mass Spectrometry -- Molecular Modelling Methods to Quantitate Drug-DNA Interactions -- Application of Anomalous Diffraction Methods to the Study of DNA and DNA-Complexes -- DNase I Footprinting -- Methods to Characterize the Effect of DNA-Modifying Compounds on Nucleosomal DNA -- REPSA: Combinatorial Approach for Identifying Preferred Drug-DNA Binding Sequences -- In vitro Transcription Assay for Resolution of Drug-DNA Interactions at Defined DNA Sequences -- In vitro Footprinting of Promoter Regions Within Supercoiled Plasmid DNA -- Topoisomerase I-Mediated DNA Relaxation as a Tool to Study Intercalation of Small Molecules into Supercoiled DNA -- A High-Throughput Assay for DNA Topoisomerases and Other Enzymes, Based on DNA Triplex Formation -- Measurement of DNA Interstrand Crosslinking in Individual Cells Using the Single Cell Gel Electrophoresis (Comet) Assay -- Measurement of DNA Interstrand Crosslinking in Naked DNA Using Gel-Based Methods -- An Evaluation Cascade for G-Quadruplex Telomere Targeting Agents in Human Cancer Cells.
  • 일반주제명
    Medicine.
    Human genetics.
    Pharmacology.
    Biomedicine.
    Pharmacology/Toxicology.
    Human Genetics.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781603274173
  • ISBN
    9781603274180
  • 언어
    영어