소장자료

Chemistry and Biology of Serpins [electronic resource]

  • Church, Frank C. editor. , Cunningham, Dennis D. editor. , Ginsburg, David. editor. , Hoffman, Maureane. editor. , Stone, Stuart R. editor. , Tollefsen, Douglas M. editor.
  • 1997
Chemistry and Biology of Serpins [electronic resource]
  • 자료유형
    단행본
  • 서명/저자사항
    Chemistry and Biology of Serpins[electronic resource] / edited by Frank C. Church, Dennis D. Cunningham, David Ginsburg, Maureane Hoffman, Stuart R. Stone, Douglas M. Tollefsen.
  • 대등서명
    Proceedings of an International Symposium held in Chapel Hill, North Carolina, April 13-16, 1996
  • 개인저자
    Church, Frank C., editor., Cunningham, Dennis D., editor., Ginsburg, David., editor., Hoffman, Maureane., editor., Stone, Stuart R., editor., Tollefsen, Douglas M., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XIX, 358 p. : online resource.
  • 총서명
    Advances in Experimental Medicine and Biology,0065-2598 ; 425
  • 내용주기
    I. Introduction -- 1. Serpins: From the Way It Was to the Way It Is -- 2. Serpins: A Mechanistic Class of Their Own -- II. Coagulation -- 3. Antithrombin: A Bloody Important Serpin -- 4. Heparin Cofactor II -- 5. PCI: Protein C Inhibitor? -- 6. Molecular Basis for the Resistance of Fibrin-Bound Thrombin to Inactivation by Heparin/Serpin Complexes -- III. Neurobiology and Cancer -- 7. Regulation of Neurons and Astrocytes by Thrombin and Protease Nexin-1: Relationship to Brain Injury -- 8. Maspin: A Tumor Suppressing Serpin -- 9. Proteases and Protease Inhibitors in Tumor Progression -- IV. Fibrinolysis -- 10. The Role of Reactive-Center Loop Mobility in the Serpin Inhibitory Mechanism -- 11. Substrate Specificity of Tissue Type Plasminogen Activator -- 12. Plasminogen Activator Inhibitor Type-2: A Spontaneously Polymerizing Serpin that Exists in Two Topological Forms -- 13. Of Mice and Men: The Function of Plasminogen Activator Inhibitors (PAIs) in Vivo -- V. Development and Reproduction -- 14. Biology of Progesterone-Induced Uterine Serpins -- 15. Serpins from an Insect, Manduca sexta -- 16. The Significance of Serpins in the Regulation of Proteases in the Male Genital Tract -- VI. Inflammation -- 17. Serpins and Programmed Cell Death -- 18. C 1 Inhibitor: Functional Analysis of Naturally-Occurring Mutant Proteins -- 19. Serp-1, a Poxvirus-Encoded Serpin, Is Expressed as a Secreted Glycoprotein that Inhibits the Inflammatory Response to Myxoma Virus Infection -- 20. Dysfunctional Variants and the Structural Biology of the Serpins -- VI. Noninhibitor Serpins -- 21. Structure-Function Studies on PEDF: A Noninhibitory Serpin with Neurotrophic Activity -- 22. Colligin, a Collagen Binding Serpin -- VII. Abstracts -- Coagulation, Neurobiology, and Cancer -- Fibrinolysis, Development, and Reproduction -- Inflammation and Noninhibitor Serpins -- Contributors.
  • 일반주제명
    Life sciences.
    Human genetics.
    Biochemistry.
    Animal physiology.
    Life Sciences.
    Biochemistry, general.
    Animal Physiology.
    Human Genetics.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781461374619
  • ISBN
    9781461553915
  • 언어
    영어