소장자료

Therapeutic Applications of Ribozymes and Riboswitches Methods and Protocols [electronic resource] :

  • Lafontaine, Daniel. editor. , Dube, Audrey. editor.
  • 2014
Therapeutic Applications of Ribozymes and Riboswitches Methods and Protocols [electronic resource] :
  • 자료유형
    단행본
  • 서명/저자사항
    Therapeutic Applications of Ribozymes and Riboswitches[electronic resource] :Methods and Protocols / edited by Daniel Lafontaine, Audrey Dube.
  • 개인저자
    Lafontaine, Daniel., editor., Dube, Audrey., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XI, 278 p. 53 illus., 19 illus. in color. : online resource.
  • 총서명
    Methods in Molecular Biology, Methods and Protocols,1064-3745 ; 1103
  • 내용주기
    Identification of Regulatory RNA in Bacterial Genomes by Genome-Scale Mapping of Transcription Start Sites -- Screening Inhibitory potential of anti-HIV RT RNA Aptamers -- Design and Evaluation of Clinically Relevant SOFA-HDV Ribozymes Targeting HIV RNA -- Directing RNase P-mediated Cleavage of Target mRNAs by Engineered External Guide Sequences in Cultured Cells -- Design and Analysis of Hammerhead Ribozyme Activity Against an Artificial Gene Target -- Knockdown Strategies for the Study of Proprotein Converstase and Proliferation in Prostate Cancer Cells -- Use of Tumor-Targeting Trans-Splicing Ribozyme for Cancer Treatment -- Characterization of Hairpin Ribozyme Reactions -- Finding Instances of Riboswitches and Ribozymes by Homology Search of Structured RNA with Infernal -- Structure-based Virtual Screening for the Identification of RNA-binding Ligands -- Probing Riboswitch Binding Sites with Molecular Docking, Focused Libraries, and in-line Probing Assays -- Discovery of Small Molecule Modifiers of microRNAs for the Treatment of HCV Infection -- Bacterial Flavin Mononucleotide Riboswitches as Targets for Flavin Analogs -- Construction and Application of Riboswitch-based Sensors That Detect Metabolites Within Bacterial Cells -- Screening Assays to Identify Artificial glmS Ribozyme Activators -- Analysis of Riboswitch Structure and Ligand Binding using Small-angle X-ray Scattering (SAXS) -- Use of SHAPE to Select 2AP Substitution sites for RNA-ligand Interactions and Dynamics Studies -- Cell Internalization SELEX:혻 In Vitro Selection for Molecules that Internalize into Cells -- DNA Electronic Switches Based on Analyte-Responsive Aptamers.
  • 일반주제명
    Medicine.
    Human genetics.
    Pharmacology.
    Biomedicine.
    Pharmacology/Toxicology.
    Human Genetics.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781627037297
  • ISBN
    9781627037303
  • 언어
    영어