소장자료

Structural Genomics and Drug Discovery Methods and Protocols [electronic resource] :

  • Anderson, Wayne F. editor.
  • 2014
Structural Genomics and Drug Discovery Methods and Protocols [electronic resource] :
  • 자료유형
    단행본
  • 서명/저자사항
    Structural Genomics and Drug Discovery[electronic resource] :Methods and Protocols / edited by Wayne F. Anderson.
  • 개인저자
    Anderson, Wayne F., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XV, 344 p. 78 illus., 64 illus. in color. : online resource.
  • 총서명
    Methods in Molecular Biology, Methods and Protocols,1064-3745 ; 1140
  • 내용주기
    Data Management in the Modern Structural Biology and Biomedical Research Environment -- Structural Genomics of Human Proteins -- Target Selection for Structural Genomics of Infectious Diseases -- Selecting Targets from Eukaryotic Parasites for Structural Genomics and Drug Discovery -- High Throughput Cloning for Biophysical Applications -- Expression and Solubility Testing in a High Throughput Environment -- Protein Production for Structural Genomics Using E. coli Expression -- Eukaryotic Expression Systems for Structural Studies -- Automated Cell-free Protein Production Methods for Structural Studies -- Parallel Protein Purification -- Oxidative Refolding from Inclusion Bodies -- High throughput Crystallization Screening -- Screening Proteins for NMR Suitability -- Salvage or Recovery of Failed Targets by in situ Proteolysis -- Salvage of Failed Protein Targets by Reductive Alkylation -- Salvage or Recovery of Failed Targets by Mutagenesis to Reduce Surface Entropy -- Data Collection for Crystallographic Structure Determination -- Structure, Determination, Refinement, and Validation -- Virtual High-Throughput Ligand Screening -- Ligand Screening using Fluorescence Thermal Shift Analysis (FTS) -- Ligand Screening using Enzymatic Assays -- Ligand Screening using NMR -- Screening Ligands by X-ray Crystallography -- Case Study ??Structural Genomics and Human Protein Kinases.
  • 일반주제명
    Medicine.
    Human genetics.
    Pharmacology.
    Biomedicine.
    Pharmacology/Toxicology.
    Human Genetics.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781493903535
  • ISBN
    9781493903542
  • 언어
    영어