소장자료

Essential concepts in clinical research : randomised controlled trials and observational epidemiology [electronic resource]

  • Schulz, Kenneth F. , Grimes, David A.
  • Elsevier
  • 2019
Essential concepts in clinical research : randomised controlled trials and observational epidemiology [electronic resource]

목차

1. An Overview of Clinical Research: The Lay of the Land
2. Descriptive Studies: What They Can and Cannot Do
3. Bias and Causal Associations in Observational Research
4. Cohort Studies: Marching Towards Outcomes
5. Case-Control Studies: Research in Reverse
6. Compared to What? Finding Controls for Case-Control Studies
7. The Limitations of Observational Epidemiology
8. Uses and Abuses of Screening Tests
9. Refining Clinical Diagnosis With Likelihood Ratios
10. Boosting Recruitment to Randomised Controlled Trials
11. Sample Size Calculations in Randomised Trials: Mandatory and Mystical
12. Generation of Allocation Sequences in Randomised Trials: Chance, Not Choice
13. Generation of Allocation Sequences in Non–Double-Blinded Randomised Trials: Guarding Against Guessing
14. Allocation Concealment in Randomised Trials: Defending Against Deciphering
15. Exclusions and Losses in Randomised Trials: Retention of Trial Participants
16. Blinding in Randomised Trials: Hiding Who Got What
17. Implementation of Treatment Blinding in Randomised Trials
18. Surrogate Endpoints and Composite Outcomes: Shortcuts to Unknown Destinations
19. Multiplicity in Randomised Trials I: Endpoints and Treatments
20. Multiplicity in Randomised Trials II: Subgroup and Interim Analyses
21. Conducting a Randomised Trial as Part of a Prospective Meta-Analysis
22. Reporting Studies in Medical Journals: CONSORT and Other Reporting Guidelines