소장자료

OPLL : ossification of the posterior longitudinal ligament [electronic resource]

  • Okawa, Atsushi editor. , Matsumoto, Morio, editor. , Iwasaki, Motoki, editor. , Kawaguchi, Yoshiharu, editor.
  • Springer
  • 2020
OPLL : ossification of the posterior longitudinal ligament [electronic resource]

초록

Ossification of the posterior longitudinal ligament (OPLL) is a hyperostotic condition of the spine with severe neurological deficits. In 1975 the Investigation Committee for OPLL, under the auspices of the Japanese Ministry of Health and Welfare, established diagnostic criteria for the condition, and with growing awareness of OPLL among Japanese researchers and spinal surgeons, the number of patients diagnosed with the condition in Japan has increased in recent years. As knowledge of OPLL has spread, there has also been an increase in the number of reported cases of the condition in other parts of the world: Asia, the United States, and Europe. Until now, however, little has been published on the subject in English; thus the appearance of this present volume is most timely. It brings together information on all aspects of OPLL - epidemiology, etiology, diagnosis, and treatment - with contributions by Japanese researchers and surgeons, including members of the Ministry of Health and Welfare Investigation Committee, and by American surgeons with expertise in the field. This collection of reports on OPLL, amply augmented with illustrations, will be of special interest to orthopedic surgeons and neurosurgeons, and to neurologists, rheumatologists, neuroradiologists, and pathologists.

목차

Part I. Introduction
1. History of Research

Part II. Epidemiology
2. An Overview of Epidemiology and Genetics
3. OPLL. Disease Entity, Prevalence, Literature Research, and Growth
4. Natural History of Ossification of the Posterior Longitudinal Ligament (OPLL)

Part III. Pathology and Pathogenesis
5. Overview of Recent Basic Researches on OPLL and OLF
6. Histopathological Features of Ossification of the Posterior Longitudinal Ligament
7. Ectopic Ossification of Human Spinal Ligaments Caused by Mesenchymal Stem Cell Abnormalities
8. A Short History of the Genetic Study of OPLL
9. Overview of Possible Roles of OPLL-Associated Genes in OPLL Development
10. Application of iPS Cell Technology for OPLL
11. Mechanisms Underlying OPLL Development in Tiptoe Walking (ttw) Mice
12. In Vivo Tracing of Neural Tracts in Tip-Toe Walking Yoshimura Mice by Diffusion Tensor Tractography
13. Metabolomics Analysis of OPLL Patients

Part IV. Diagnosis
14. Diagnosis of OPLL and OLF. Overview
15. Clinical Manifestation of Cervical OPLL
16. Three-Dimensional Imaging of Cervical Ossification of the Posterior Longitudinal Ligament
17. Clinical Manifestations of Thoracic Ossification of the Posterior Longitudinal Ligament (OPLL) and Ossification of the Ligament Flavum (OLF)
18. Evaluation of Distribution Patterns of Spinal Ligament Ossification Using Whole-Spine Computed Tomography in Patients with Cervical Ossification of the Posterior Longitudinal Ligament
19. Diagnostic Imaging of Thoracic OPLL and OLF
20. Biomechanics of the Spinal Cord Compression Due to Cervical Ossification of the Posterior Longitudinal Ligament

Part V. Treatment
21. Surgical Indications and Choice of Surgical Procedure for Cervical Ossification of the Longitudinal Ligament
22. Overview of Laminoplasty
23. Open-Door Laminoplasty for Cervical OPLL. Technique, Long-Term Results, and Complications
24. Double-Door Laminoplasty for Cervical OPLL. Technique, Complications, and Long-Term Results
25. Posterior Decompression and Fusion for Cervical OPLL. Indication and Technique
26. Anterior Cervical Decompression for Cervical OPLL. Technique, Complications, and Long-Term Results
27. Surgical Indications and Choice of Surgical Procedure for Thoracic OPLL
28. Posterior Decompression and Fusion for Thoracic OPLL. Surgical Techniques, Outcomes, Timing, and Complications
29. Anterior Decompression and Fusion for Thoracic OPLL. Transthoracic and Transsternal Approaches
30. Circumferential Decompression Through Posterior Approach for Thoracic OPLL. Technique and Complications
31. Surgery for Ossification of the Ligamentum Flavum. Posterior Decompression with or Without Fusion
32. Computer-Aided Surgery for Ossification of the Spinal Ligaments
33. Surgical Treatment of Thoracic Ossification of the Posterior Longitudinal Ligament. Intraoperative Spinal Cord Monitoring
34. Intraoperative Ultrasonography for Patients with Ossification of the Posterior Longitudinal Ligament