소장자료

Apoptosis, Senescence, and Cancer [electronic resource]

  • Gewirtz, David A. editor. , Holt, Shawn E. editor. , Grant, Steven. editor.
  • 2007
Apoptosis, Senescence, and Cancer [electronic resource]
  • 자료유형
    단행본
  • 서명/저자사항
    Apoptosis, Senescence, and Cancer[electronic resource] / edited by David A. Gewirtz, Shawn E. Holt, Steven Grant.
  • 개인저자
    Gewirtz, David A., editor., Holt, Shawn E., editor., Grant, Steven., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XVII, 599 p. 69 illus., 5 illus. in color. : online resource.
  • 총서명
    Cancer Drug Discovery and Development
  • 내용주기
    Apoptosis and Alternative Modes of Cell Death -- The Intrinsic Pathway of Apoptosis -- The Extrinsic Pathway of Apoptosis -- Evaluating the Importance of Apoptosis and Other Determinants of Cell Death and Survival -- Mitotic Catastrophe -- Autophagy and Autophagic Cell Death -- Regulation and Function of Detachment-Induced Cell Death (Anoikis) in Cancer Progression and Metastasis -- Telomeres and Telomerase, Senescence, Genomic Instability, and Tumorigenesis -- Structure and Function of the Telomere -- Overview of Senescence -- Contributions of Telomerase to Tumorigenesis -- The Role of Telomeres in Genomic Instability -- DNA Damage Response, Signaling Pathways, and Tumorigenesis -- Overview of the DNA Damage Checkpoint -- Interactions Between Myc- and Cyclin-Dependent Kinase Inhibitors in Cancer -- Interplay Between ?H2AX and 53BP1 Pathways in DNA Double-Strand Break Repair Response -- DNA-Dependent Protein Kinase in Repair, Apoptosis, Telomere Maintenance, and Chemotherapy -- Resistance and Sensitization -- Resistance/Signaling Pathways -- Ceramide and Multidrug Resistance -- Chemo- and Radiosensitization Through Inhibition of PI3K/Akt Signaling -- The Advancement of Epidermal Growth Factor Receptor Inhibitors in Cancer Therapy -- Established Cancer Therapies -- Antimetabolites -- Topoisomerase I Poisons and Apoptotic Topoisomerase I-DNA Complexes -- Perturbations of Cellular Functions by Topoisomerase II Inhibitors -- The Significance of Poly-Targeting in Apoptosis Induction by Alkylating Agents and Platinum Drugs -- Contributions of Apoptosis and Senescence to Cytotoxicity Produced by Microtubule-Stabilizing Agents -- Tyrosine Kinase Inhibitors -- Recent and Developing Cancer Therapies -- Monoclonal Antibodies in Lymphomas -- Role of Apoptosis in Anti-Angiogenic Cancer Therapies -- Photodynamic Therapy-Induced Apoptosis -- Modulation of TRAIL Signaling for Cancer Therapy.
  • 일반주제명
    Medicine.
    Cancer research.
    Pharmacology.
    Nuclear medicine.
    Radiotherapy.
    Oncology.
    Medicine & Public Health.
    Radiotherapy.
    Cancer Research.
    Oncology.
    Nuclear Medicine.
    Pharmacology/Toxicology.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781588295279
  • ISBN
    9781597452212
  • 언어
    영어