소장자료

DNA Topoisomerases and Cancer [electronic resource]

  • Pommier, Yves. editor.
  • 2012
DNA Topoisomerases and Cancer [electronic resource]
  • 자료유형
    단행본
  • 서명/저자사항
    DNA Topoisomerases and Cancer[electronic resource] / edited by Yves Pommier.
  • 판차
    1.
  • 개인저자
    Pommier, Yves., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XI, 443 p. 65 illus., 49 illus. in color. : online resource.
  • 총서명
    Cancer Drug Discovery and Development,2196-9906
  • 내용주기
    Introduction and Historical Perspective -- Human DNA topoisomerase I: Structure, Enzymology and Biology -- Mitochondrial topoisomerases -- Structure and mechanism of eukaryotic type IIA topoisomerases -- Essential functions of topoisomerase III in the nucleus and mitochondria -- DNA topoisomerase I and illegitimate recombination -- Topoisomerase-induced DNA damage -- Topoisomerases and carcinogenesis: Topo III and BLM -- Topoisomerase inhibitors: a paradigm for interfacial inhibitors -- Topoisomerase I inhibitors: chemical biology -- Topoisomerase II inhibitors: chemical biology -- Topoisomerase I inhibitors: current use and prospects -- Topoisomerase II inhibitors: current use and prospects -- Transcription stress by camptothecin: mechanism and implication for the drug antitumor activity -- Mechanism regulating cellular responses to DNA topoisomerase I-targeted agents -- Tyrosyl-DNA-phosphodiesterase -- Ubiquitin and ubiquitin-like proteins in repair of topoisomerase-mediated DNA damage -- Repair of topoisomerase II-mediated DNA damage: fixing DNA damage arising from a protein covalently trapped on DNA -- Topoisomerases and Apoptosis -- Index.
  • 일반주제명
    Medicine.
    Cancer research.
    Pharmacology.
    Biomedicine.
    Cancer Research.
    Pharmacology/Toxicology.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781461403227
  • ISBN
    9781461403234
  • 언어
    영어