소장자료

Fragment-Based Methods in Drug Discovery [electronic resource]

  • Klon, Anthony E. editor.
  • 2015
Fragment-Based Methods in Drug Discovery [electronic resource]
  • 자료유형
    단행본
  • 서명/저자사항
    Fragment-Based Methods in Drug Discovery[electronic resource] / edited by Anthony E. Klon.
  • 개인저자
    Klon, Anthony E., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    IX, 230 p. 68 illus., 53 illus. in color. : online resource.
  • 총서명
    Methods in Molecular Biology,1064-3745 ; 1289
  • 내용주기
    Solvation Methods for Protein-Ligand Docking -- Binding Site Druggability Assessment in Fragment-Based Drug Design -- Generating "Fragment-Based Virtual Library" Using Pocket Similarity Search of Ligand-Receptor Complexes -- Virtual Fragment Preparation for Computational Fragment-Based Drug Design -- Fragment Library Design: Using Cheminformatics and Expert Chemists to Fill Gaps in Existing Fragment Libraries -- Protocol for Fragment Hopping -- Site Identification by Ligand Competitive Saturation (SILCS) Simulations for Fragment-Based Drug Design -- A Computational Fragment-Based De Novo Design Protocol Guided by Ligand Efficiency Indices (LEI) -- Scoring Functions for Fragment-Based Drug Discovery -- Computational Methods for Fragment-Based Ligand Design: Growing and Linking -- Design Strategies for Computational Fragment-Based Drug Design -- Protein Binding Site Analysis for Drug Discovery Using a Computational Fragment-Based Method -- Fragment-Based Design of Kinase Inhibitors: A Practical Guide -- Designing a Small Molecule Erythropoietin Mimetic -- Designing an Orally Available Non-Toxic p38 Inhibitor with a Fragment-Based Strategy.
  • 일반주제명
    Medicine.
    Pharmacology.
    Biomedicine.
    Pharmacology/Toxicology.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781493924851
  • ISBN
    9781493924868
  • 언어
    영어