소장자료

In Silico Methods for Predicting Drug Toxicity [electronic resource]

  • Benfenati, Emilio. editor.
  • 2016
In Silico Methods for Predicting Drug Toxicity [electronic resource]
  • 자료유형
    단행본
  • 서명/저자사항
    In Silico Methods for Predicting Drug Toxicity[electronic resource] / edited by Emilio Benfenati.
  • 개인저자
    Benfenati, Emilio., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XI, 534 p. 193 illus., 156 illus. in color. : online resource.
  • 총서명
    Methods in Molecular Biology,1064-3745 ; 1425
  • 내용주기
    QSAR Methods -- In Silico 3D-Modelling of Binding Activities -- Modeling Pharmacokinetics -- Modeling ADMET -- In Silico Prediction of Chemically-Induced Mutagenicity: How to Use QSAR Models and Interpret Their Results -- In Silico Methods for Carcinogenicity Assessment -- VirtualToxLab: Exploring the Toxic Potential of Rejuvenating Substances Found in Traditional Medicines -- In Silico Model for Developmental Toxicity: How to Use QSAR Models and Interpret Their Results -- In Silico Models for Repeated Dose Toxicity (RDT): Prediction of the No Observed Adverse Effect Level (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) for Drugs -- In Silico Models for Acute Systemic Toxicity -- In Silico Models for Hepatotoxicity -- In Silico Models for Ecotoxicity of Pharmaceuticals -- Use of Read-Across Tools -- Adverse Outcome Pathways as Tools to Assess Drug-Induced Toxicity -- A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure -- In Silico Study of In Vitro GPCR Assays by QSAR Modeling -- Taking Advantage of Databases -- QSAR Models at the United States FDA/NCTR -- A Round Trip from Medicinal Chemistry to Predictive Toxicology -- The Use of In Silico Models Within a Large Pharmaceutical Company -- The Consultancy Activity on In Silico Models for Genotoxic Prediction of Pharmaceutical Impurities.
  • 일반주제명
    Medicine.
    Pharmacology.
    Biomedicine.
    Pharmacology/Toxicology.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781493936076
  • ISBN
    9781493936090
  • 언어
    영어