소장자료

Proteomics for Drug Discovery Methods and Protocols [electronic resource] :

  • Lazar, Iulia M. editor. , Kontoyianni, Maria. editor. , Lazar, Alexandru C. editor.
  • 2017
Proteomics for Drug Discovery Methods and Protocols [electronic resource] :
  • 자료유형
    단행본
  • 서명/저자사항
    Proteomics for Drug Discovery[electronic resource] :Methods and Protocols / edited by Iulia M. Lazar, Maria Kontoyianni, Alexandru C. Lazar.
  • 개인저자
    Lazar, Iulia M., editor., Kontoyianni, Maria., editor., Lazar, Alexandru C., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XI, 302 p. 62 illus., 46 illus. in color. : online resource.
  • 총서명
    Methods in Molecular Biology,1064-3745 ; 1647
  • 내용주기
    A Photoaffinity Labeling-Based Chemoproteomics Strategy for Unbiased Target Deconvolution of Small Molecule Drug Candidates -- Multiplexed Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry Quantification of Cancer Signaling Proteins -- Monitoring Dynamic Changes of the Cell Surface Glycoproteome by Quantitative Proteomics -- High Resolution Parallel Reaction Monitoring with Electron Transfer Dissociation for Middle-Down Proteomics: An Application to Study the Quantitative Changes Induced by Histone Modifying Enzyme Inhibitors and Activators -- Preparation and Immunoaffinity Depletion of Fresh Frozen Tissue Homogenates for Mass Spectrometry-Based Proteomics in the Context of Drug Target/Biomarker Discovery -- Target Identification Using Cell Permeable and Cleavable Chloroalkane Derivatized Small Molecules -- Microfluidics-Mass Spectrometry of Protein-Carbohydrate Interactions: Applications to Development of Therapeutics and Biomarker Discovery -- Studying Protein-Protein Interactions by Biotin AP-Tagged Pulldown and LTQ-Orbitrap Mass Spectrometry -- Post-Translational Modification Profiling-Functional Proteomics for the Analysis of Immune Regulation -- Reverse Phase Protein Arrays and Drug Discovery -- Probing Protein Kinase-ATP Interactions Using a Fluorescent ATP Analog -- Preparation of Disease-Related Protein Assemblies for Single Particle Electron Microscopy -- Identification of Lipid-Binding Modulators Using the Protein-Lipid Overlay Assay -- Resazurin Live Cell Assay: Setup and Fine-Tuning for Reliable Cytotoxicity -- Exploring Protein-Protein Interactions as Drug Targets for Anti-Cancer Therapy with In Silico Workflows -- Method to Identify Silent Codon Mutations that May Alter Peptide Elongation Kinetics and Co-Translational Protein Folding -- In Silico Design of Anticancer Peptides -- Docking and Virtual Screening in Drug Discovery -- Bioinformatics Resources for Interpreting Proteomics Mass Spectrometry Data.
  • 일반주제명
    Medicine.
    Pharmacology.
    Biomedicine.
    Pharmacology/Toxicology.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781493972005
  • ISBN
    9781493972012
  • 언어
    영어