25 Years of p53 Research [electronic resource]

  • Hainaut, Pierre. editor. , Wiman, Klas G. editor.
  • 2005
25 Years of p53 Research [electronic resource]
  • 자료유형
  • 서명/저자사항
    25 Years of p53 Research[electronic resource] / edited by Pierre Hainaut, Klas G. Wiman.
  • 개인저자
    Hainaut, Pierre., editor., Wiman, Klas G., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    XII, 446 p. : online resource.
  • 내용주기
    The First Twenty-Five Years of p53 Research -- Regulation of p53 DNA Binding -- 20 Years of DNA Damage Signaling to p53 -- Gatekeepers of the Guardian: p53 Regulation by Post-Translational Modification, MDM2 and MDMX -- Regulation of the p53 Response by Cellular Growth and Survival Factors -- P53, Cell Cycle Arrest and Apoptosis -- P53 Has a Direct Pro-apoptotic Action at the Mitochondria -- Manipulating the p53 Gene in the Mouse: Organismal Functions of a Prototype Tumor Suppressor -- P53, P63, and P73: Internecine Relations? -- P73, P63 and Mutant P53: Members of Protein Complexs Floating in Cancer Cells -- P53: Gatekeeper, Caretaker or Both? -- Analysis of p53 Gene Alterations in Cancer: A Critical View -- Patterns of TP53 Mutations in Human Cancer: Interplay Between Mutagenesis, DNA Repair and Selection -- Prognostic and Predictive Value of TP53 Mutations in Human Cancer -- P53 Links Tumor Development to Cancer Therapy -- Novel p53-Based Therapies: Strategies and Future Prospects -- Wild Type p53 Conformation, Structural Consequences of p53 Mutations and Mechanisms of Mutant p53 Rescue -- Mutant p53 Reactivation as a Novel Strategy for Cancer Therapy -- Novel Approaches to p53-Based Therapy: ONYX-015 -- p53 as Seen by an Outsider.
  • 일반주제명
    Cancer research.
    Molecular biology.
    Life sciences.
    Cancer Research.
    Molecular Medicine.
    Biomedicine general.
    Life Sciences, general.
  • 기본자료 저록
    Springer eBooks
  • 기타형태 저록
    Printed edition: 9781402029202
  • ISBN
  • 언어