E-Book

eQTL Analysis: Methods and Protocols [electronic resource]

  • Shi, Xinghua Mindy. editor.
  • Humana
  • 2020
eQTL Analysis: Methods and Protocols [electronic resource]
  • 자료유형
    단행본
  • 서명/저자사항
    eQTL Analysis:Methods and Protocols[electronic resource] / edited by Xinghua Mindy Shi.
  • 판차
    1st ed.
  • 발행사항
    New York : Humana, 2020.
  • 개인저자
    Shi, Xinghua Mindy., editor.
  • 단체저자
    SpringerLink (Online service)
  • 형태사항
    X, 252 p. 145 illus., 65 illus. in color. .
  • 총서명
    Methods in Molecular Biology,1064-3745 ; 2082
  • 내용주기
    Introductory Methods for eQTL Analyses -- Performing QTL and eQTL Analyses with the R-package GenomicTools -- eQTL Mapping using Transcription Factor Affinity -- Identification and Quantification of Splicing Quantitative Trait Loci -- Genome-wide Composite Interval Mapping (GCIM) of Expressional Quantitative Trait Loci in Backcross Population -- Combining eQTL and SNP Annotation Data to Identify Functional Noncoding SNPs in GWAS Trait-associated Regions -- Statistical and Machine Learning Methods for eQTL Analysis -- Sparse Regression Models for Unraveling Group and Individual Associations in eQTL Mapping -- Exploring Bayesian Approaches to eQTL Mapping through Probabilistic Programming -- High-order Association Mapping for Expression Quantitative Trait Loci -- Integration of Multi-omics Data for Expression Quantitative Trait Loci (eQTL) Analysis and eQTL Epistasis -- Sparse Partial Least Squares Methods for Joint Modular Pattern Discovery -- Expression Quantitative Trait Loci (eQTL) Analysis in Cancer -- QTL Analysis Beyond eQTLs -- Quantitative Trait Loci (QTL) Mapping -- Expression Quantitative Trait Loci Analysis in Multiple Tissues -- Tissue Specific eQTL in Zebrafish. .
  • 일반주제명
    Bioinformatics.
    Genetics.
  • 기본자료 저록
    Springer eBooks
  • ISBN
    9781071600269
  • 언어
    영어

초록

This volume details state-of-art eQTL analysis, where interdisciplinary researchers are provided both theoretical and practical guidance to eQTL analysis and interpretation. Chapters guide readers through methods and tools for eQTL and QTL analysis and the usage of such analysis in various scenarios. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, eQTL Analysis: Methods and Protocols to ensure successful results in the further study of this vital field