Biomarkers for Alzheimer's Disease Drug Development [electronic resource]

  • Perneczky, Robert. editor.
  • 2018
Biomarkers for Alzheimer's Disease Drug Development [electronic resource]
  • Data Type
  • Title/Author
    Biomarkers for Alzheimer's Disease Drug Development[electronic resource] / edited by Robert Perneczky.
  • Author
    Perneczky, Robert., editor.
  • Authors
    SpringerLink (Online service)
  • Phy Desc.
    XV, 372 p. 54 illus., 45 illus. in color. : online resource.
  • Total State.
    Methods in Molecular Biology,1064-3745 ; 1750
  • Contents Note
    Epidemiology of Dementia: The Burden on Society, the Challenges for Research -- Population-based Approaches to Alzheimer?셲 Disease Prevention -- Systems Biology Methods for Alzheimer?셲 Disease Research towards Molecular Signatures, Subtypes and Stages and Precision Medicine. Application in Cohort Studies and Trials -- CSF Lipidomics Analysis: High-Resolution Mass Spectrometry Analytical Platform -- CSF N-glycomics using MALDI MS Techniques in Alzheimer?셲 Disease -- MicroRNA Profiling of Alzheimer?셲 Disease Cerebrospinal Fluid -- Validation of a Chemiluminescence Immunoassay for Measuring 혻Amyloid-棺 in Human Blood Plasma -- Mass Spectrometry-based Metabolomic Multiplatform for Alzheimer?셲 Disease Research -- Blood-based Biomarker Screening with Agnostic Biological Definitions for an Accurate Diagnosis within the Dimensional Spectrum of Neurodegenerative Diseases -- Functional Magnetic Resonance Imaging in Alzheimer??Disease Drug Development -- Neuroimaging Methods for MRI Analysis in CSF Biomarkers Studies -- Hybrid PET-MRI in Alzheimer?셲 Disease Research -- Amyloid PET Imaging: Standardization and Integration with Other Alzheimer Disease Biomarkers -- The use of 18F-FDG PET in the Diagnostic Workup of Alzheimer?셲 Dementia -- Quantification of Tau Load in Alzheimer?셲 Disease Clinical Trials Using Positron Emission Tomography -- Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach -- Unbiased Lipidomics and Metabolomics of Human Brain Samples -- Neuropathological Assessment as an Endpoint in Clinical Trial Design -- Analysis of micro-RNA Expression by qPCR on a Microfluidics Platform for Alzheimer?셲 Disease Biomarker Discovery -- Telomere length shortening in Alzheimer?셲 disease ??procedures for a causal investigation using single nucleotide polymorphisms in a Mendelian Randomization study -- Quantifying miRNA Deregulation in Alzheimer?셲 Disease -- Imaging of Microglial Activation in Alzheimer?셲 Disease by [11C]PBR28 PET -- In Vivo Two-photon Calcium Imaging of Hippocampal Neurons in Alzheimer Mouse Models -- Cognitive Assessment in Alzheimer?셲 Disease Clinical Trials -- Data Mining and Machine Learning Methods for Dementia Research.혻.
  • Topical Term
  • Host Item
    Springer eBooks
  • Additional Item
    Printed edition: 9781493977031
  • ISBN
  • Language