Mouse Models for Drug Discovery Methods and Protocols [electronic resource] :

  • Proetzel, Gabriele. editor. , Wiles, Michael V. editor.
  • 2016
Mouse Models for Drug Discovery Methods and Protocols [electronic resource] :
  • Data Type
  • Title/Author
    Mouse Models for Drug Discovery[electronic resource] :Methods and Protocols / edited by Gabriele Proetzel, Michael V. Wiles.
  • Edition
    2nd ed. 2016.
  • Author
    Proetzel, Gabriele., editor., Wiles, Michael V., editor.
  • Authors
    SpringerLink (Online service)
  • Phy Desc.
    XI, 436 p. 63 illus., 37 illus. in color. : online resource.
  • Total State.
    Methods in Molecular Biology,1064-3745 ; 1438
  • Contents Note
    Genetically Defined Strains in Drug Development and Toxicity Testing -- Simple, Efficient CRISPR-Cas9 Mediated Gene Editing in Mice: Strategies and Methods -- Mouse Sperm Cryopreservation and Recovery of Genetically Modified Mice -- Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells -- Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens -- Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies -- A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics -- Germ-Free Mice Model for Studying Host-Microbial Interactions -- Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans -- Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery -- Cholesterol Absorption and Metabolism -- Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening -- Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research -- Murine Model for Colitis-Associated Cancer of the Colon -- Mouse Models for Studying Depression-Like States and Antidepressant Drugs -- Experimental Models of Anxiety for Drug Discovery and Brain Research -- Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders -- Better Utilization of Mouse Models of Neurodegenerative Diseases in Preclinical Studies: From the Bench to the Clinic -- Neuromuscular Disease Models and Analysis -- Brightfield Imaging and Optical Coherence Tomography of the Mouse Posterior Eye -- Mouse Models as Tools to Identify Genetic Pathways for Retinal Degeneration, as Exemplified by Leber's Congenital Amaurosis.
  • Topical Term
  • Host Item
    Springer eBooks
  • Additional Item
    Printed edition: 9781493936595
  • ISBN
  • Language