Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols [electronic resource] :

  • Orzaez, Mar. editor. , Sancho Medina, Monica. editor. , Perez-Paya, Enrique. editor.
  • 2016
Cyclin-Dependent Kinase (CDK) Inhibitors Methods and Protocols [electronic resource] :
  • Data Type
  • Title/Author
    Cyclin-Dependent Kinase (CDK) Inhibitors[electronic resource] :Methods and Protocols / edited by Mar Orzaez, Monica Sancho Medina, Enrique Perez-Paya.
  • Edition
    1st ed. 2016.
  • Author
    Orzaez, Mar., editor., Sancho Medina, Monica., editor., Perez-Paya, Enrique., editor.
  • Authors
    SpringerLink (Online service)
  • Phy Desc.
    X, 227 p. 42 illus., 22 illus. in color. : online resource.
  • Total State.
    Methods in Molecular Biology,1064-3745 ; 1336
  • Contents Note
    Immunoprecipitation of CDK-Cyclin Complexes for Determination of Kinase Activity -- Expression and Purification of Recombinant Cyclins and CDKs for Activity Evaluation -- Expression and Purification of Recombinant CDKs: CDK7, CDK8 and CDK9 -- Preparation of CDK/Cyclin Inhibitor Complexes for Structural Determination -- Fragment-Based De Novo Design of Cyclin-Dependent Kinase 2 Inhibitors -- 혻Protein-Protein Interaction Inspire the De Novo Design of Cyclin-Dependent Kinases Peptide Inhibitors -- Identification of Cyclin A Binders with a Fluorescent Peptide Sensor -- Cell Synchronization Techniques to Study the Action of CDK Inhibitors -- Analysis of CDK Inhibitors Action on Mitochondria-Mediated Apoptosis -- Evaluating the Effects of CDK Inhibitors in Ischemia-Reperfusion Injury Models -- Assessing Cell Cycle Independent Function of the CDK Inhibitor p21CDKN1A in DNA Repair -- Drug Delivery Strategies of Chemical CDK Inhibitors -- Animal Models for Studying the In Vivo Functions of Cell Cycle CDKs -- Evaluating Chemical CDK Inhibitors as Cell Death Inducers -- Models for the Study of the Crosstalk between Inflammation and Cell Cycle -- Metabolomic Applications to the Characterization of the Mode-of-Action of CDK Inhibitors.
  • Topical Term
  • Host Item
    Springer eBooks
  • Additional Item
    Printed edition: 9781493929252
  • ISBN
  • Language