E-Book

Novel Anticancer Drug Protocols [electronic resource]

  • Buolamwini, John K. editor. , Adjei, Alex A. editor.
  • 2003
Novel Anticancer Drug Protocols [electronic resource]
  • Data Type
    Book
  • Title/Author
    Novel Anticancer Drug Protocols[electronic resource] / edited by John K. Buolamwini, Alex A. Adjei.
  • Author
    Buolamwini, John K., editor., Adjei, Alex A., editor.
  • Authors
    SpringerLink (Online service)
  • Phy Desc.
    XVI, 355 p. : online resource.
  • Total State.
    Methods in Molecular Medicine,1543-1894 ; 85
  • Contents Note
    Overview of Novel Anticancer Drug Targets -- Kinase Inhibitor Discovery Protocols -- Biomarker Assays for Phosphorylated MAP Kinase -- Assays for Cyclin-Dependent Kinase Inhibitors -- Identifying Inhibitors of ATM and ATR Kinase Activities -- Angiogenesis and Metastasis Protocols -- The Rat Aortic Ring Assay for In Vitro Study of Angiogenesis -- Real Time In Vivo Quantitation of Tumor Angiogenesis -- Use of Tumor-Activated Hepatic Stellate Cell as a Target for the Preclinical Testing of Anti-Angiogenic Drugs Against Hepatic Tumor Development -- Cell Motility, Adhesion, Homing, and Migration Assays in the Studies of Tyrosine Kinases -- Inflammatory Response of Tumor-Activated Hepatic Sinusoidal Endothelium as a Target for the Screening of Metastasis Chemopreventive Drugs -- Binding Assay for Selectins -- Determination of Peak Serum Levels and Immune Response to the Humanized Anti-Ganglioside Antibody-Interleukin-2 Immunocytokine -- Immunohistochemical Assays in the Clinical Setting -- Immunohistochemical Determination of EGFR-Tyrosine Kinase Inhibition in Clinical Samples -- Immunohistochemical Assays of Farnesyltransferase Inhibition in Patient Samples -- Protein Chaperoning/Degradation Protocols -- Assays for HSP90 and Inhibitors -- Assays for Proteasome Inhibition -- Protein-Protein and Protein-DNA Interactions -- The Mammalian Two-Hybrid Assay for Detection of Coactivator-Nuclear Receptor Interactions -- Preparation of DNA-Protein Complexes Suitable for Spectroscopic Analysis -- Antisense -- Antisense Oligonucleotide Inhibitors of MDM2 Oncogene Expression -- Genomics -- Pharmacogenetic Analysis of Clinically Relevant Genetic Polymorphisms -- Gene Expression Microarrays -- Methods for Isolation and Genetic Analysis of Circulating Tumor DNA in Patient Plasma -- Cell Lifespan/Longevity -- The Use of Early Sea Urchin Embryos in Anticancer Drug Testing -- In Vivo Imaging -- PET Screening of Anticancer Drugs -- Miscellaneous Protocols -- Assays for In Vitro and In Vivo Synergy -- Flow Cytometric Methods for Detection and Quantification of Apoptosis -- Assays for Neoplastic Cell Enrichment in Bone Marrow Samples.
  • Topical Term
    Pharmacy.
    Pharmacy.
    Pharmacy.
  • Host Item
    Springer eBooks
  • Additional Item
    Printed edition: 9780896039636
  • ISBN
    9781592593804
  • Language
    English