E-Book

Neocarzinostatin The Past, Present, and Future of an Anticancer Drug [electronic resource] :

  • Maeda, Hiroshi. editor. , Edo, Kiyoto. editor. , Ishida, Nakao. editor.
  • 1997
Neocarzinostatin The Past, Present, and Future of an Anticancer Drug [electronic resource] :
  • Data Type
    Book
  • Title/Author
    Neocarzinostatin[electronic resource] :The Past, Present, and Future of an Anticancer Drug / edited by Hiroshi Maeda, Kiyoto Edo, Nakao Ishida.
  • Author
    Maeda, Hiroshi., editor., Edo, Kiyoto., editor., Ishida, Nakao., editor.
  • Authors
    SpringerLink (Online service)
  • Phy Desc.
    XVI, 287 p. 58 illus., 13 illus. in color. : online resource.
  • Contents Note
    Chemical Structure of the Apoprotein of Neocarzinostatin -- Neocarzinostatin Chromophore: Structure and Mechanism of DNA Cleavage -- Synthesis and Chemistry of Nine-Membered Cyclic Enediyne Chromophores of Chromoprotein Antitumor Antibiotics -- Solution Structure of Neocarzinostatin Determined by Homonuclear Two-Dimensional Nuclear Magnetic Resonance -- Three-Dimensional Structure of Neocarzinostatin -- The Biochemical Mechanisms Involved in the Biological Effects Induced by Neocarzinostatin (NCS) and the NCS Chromophore -- Activation of Neocarzinostatin by NADPH Cytochrome P-450 Reductase: Proposal of an Ultimate Mode of Action in Cells Involving Oxygen Free Radicals -- Immunomodulating Antitumor Mechanisms of SMANCS -- Host-Mediated Antitumor Activity Induced by Neocarzinostatin and Its Polymer-Conjugated Derivative in Tumor-Bearing Mice -- Pharmacological Uniqueness and Clinical Effects of Neocarzinostatin -- Metamorphosis of Neocarzinostatin to SMANCS: Chemistry, Biology, Pharmacology, and Clinical Effect of the First Prototype Anticancer Polymer Therapeutic -- Supplementary Materials: Publications on Neocarzinostatin or Related Subjects, in English, 1960??981.
  • Topical Term
    Medicine.
    Cancer research.
    Biomedicine.
    Cancer Research.
  • Host Item
    Springer eBooks
  • Additional Item
    Printed edition: 9784431669166
  • ISBN
    9784431669142
  • Language
    English