E-Book

Structural Bioinformatics: Methods and Protocols [electronic resource]

  • Gáspári, Zoltán. editor.
  • Humana
  • 2020
Structural Bioinformatics: Methods and Protocols [electronic resource]
  • Data Type
    Book
  • Title/Author
    Structural Bioinformatics:Methods and Protocols[electronic resource] / edited by Zoltán Gáspári.
  • Edition
    1st ed.
  • Publication
    New York, NY : Humana, 2020.
  • Author
    Gáspári, Zoltán., editor., edt, http://id.loc.gov/vocabulary/relators/edt
  • Authors
    SpringerLink (Online service)
  • Phy Desc.
    XII, 256 p. 86 illus., 76 illus. in color. .
  • Total State.
    Methods in Molecular Biology,1064-3745 ; 2112
  • Contents Note
    Visualization and Analysis of Protein Structures with LiteMol Suite -- Comparative Protein Structure Analysis with Bio3D-Web -- Using DALI for Protein Structure Comparison -- Assessing Protein Function through Structural Similarities with CATH -- Protein Thermal Stability Engineering using HoTMuSiC -- Contact Area-Based Structural Analysis of Proteins and their Complexes using CAD-Score -- A Comprehensive Computational Platform to Guide Drug Development using Graph-Based Signature Methods -- Systematic Exploration of Binding Modes of Ligands on Drug Targets -- Using MemBlob to Analyze Transmembrane Regions Based on Cryo-EM Maps -- Structural Characterization of Protein-Protein Interactions with pyDockSAXS -- Protein-Protein Modeling using Cryo-EM Restraints -- Modeling of Multimolecular Complexes -- Biological Assembly Comparison with VAST+ -- BioMagResBank (BMRB) as a Resource for Structural Biology -- Integrating Molecular Simulation and Experimental Data: A Bayesian/Maximum Entropy Reweighting Approach -- Evaluation and Selection of Dynamic Protein Structural Ensembles with CoNSEnsX+.
  • Topical Term
    Bioinformatics.
    Bioinformatics. http://scigraph.springernature.com/things/product-market-codes/L15001
  • Host Item
    Springer eBooks
  • Additional Item
    Printed edition: 9781071602690
  • ISBN
    9781071602706
  • Language
    English

Abstract

This volume looks at the latest techniques used to perform comparative structure analyses, and predict and evaluate protein-ligand interactions. The chapters in this book cover tools and servers such as LiteMol; Bio3D-Web; DALI; CATH; HoTMuSiC, a contact-base protein structure analysis tool known as CAD-Score; PyDockSaxs and HADDOCK; CombDock and DockStar; the BioMagResBank database; as well as BME and CoNSEnsX+. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Structural Bioinformatics: Methods and Protocols is a practical guide for researchers to learn more about the aforementioned tools to further enhance their studies in the growing field of structural bioinformatics. Chapter 13 is open access under a CC-BY 4.0 license via link.springer.com.